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Clonal haematopoiesis and dysregulation of the immune system - Nature Reviews Immunology

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Clonal haematopoiesis and dysregulation of the immune system - Nature Reviews Immunology

Age-related diseases are frequently linked to pathological immune dysfunction, including excessive inflammation, autoreactivity and immunodeficiency. Recent analyses of human genetic data have revealed that somatic mutations and mosaic chromosomal alterations in blood cells — a condition known as clonal haematopoiesis (CH) — are associated with ageing and pathological immune dysfunction.

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Clonal haematopoiesis and dysregulation of the immune system - Nature Reviews Immunology

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Clonal haematopoiesis and dysregulation of the immune system - Nature Reviews Immunology

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