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Immune checkpoint blockade breaches the mucosal firewall to induce gut microbiota translocation - Nature Reviews Immunology

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Immune checkpoint blockade breaches the mucosal firewall to induce gut microbiota translocation - Nature Reviews Immunology

Choi et al. show that in mice with melanoma, immune checkpoint blockade therapy increases the translocation of live intestinal bacteria to extraintestinal sites through dendritic cell activation and lymph node remodelling.

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Immune checkpoint blockade breaches the mucosal firewall to induce gut microbiota translocation - Nature Reviews Immunology

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Immune checkpoint blockade breaches the mucosal firewall to induce gut microbiota translocation - Nature Reviews Immunology

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