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ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells - Nature Structural & Molecular Biology

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ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells - Nature Structural & Molecular Biology

Cohesins are ancient and ubiquitous regulators of chromosome architecture and function, but their diverse roles and regulation remain poorly understood. During meiosis, chromosomes are reorganized as linear arrays of chromatin loops around a cohesin axis. This unique organization underlies homolog pairing, synapsis, double-stranded break induction, and recombination.

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atm cohesins meiotic cells cell biology biology microbiology

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ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells - Nature Structural & Molecular Biology

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ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells - Nature Structural & Molecular Biology

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