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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells - Nature Communications

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells - Nature Communications

Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. The cell subpopulation in the lineage hierarchy that serves as cell of origin for the different TC histotypes is unknown. Human embryonic stem cells (hESCs) with appropriate in vitro stimulation undergo sequential differentiation into thyroid progenitor cells (TPCs-day 22), which maturate into thyrocytes (day 30).

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells - Nature Communications

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells - Nature Communications

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