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Microbiota alters the metabolome in an age- and sex- dependent manner in mice - Nature Communications

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Microbiota alters the metabolome in an age- and sex- dependent manner in mice - Nature Communications

Commensal bacteria are major contributors to mammalian metabolism. We used liquid chromatography mass spectrometry to study the metabolomes of germ-free, gnotobiotic, and specific-pathogen-free mice, while also evaluating the influence of age and sex on metabolite profiles. Microbiota modified the metabolome of all body sites and accounted for the highest proportion of variation within the gastrointestinal tract.

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health microbiota metabolomes sex mice science biology microbiology

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Microbiota alters the metabolome in an age- and sex- dependent manner in mice - Nature Communications

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Microbiota alters the metabolome in an age- and sex- dependent manner in mice - Nature Communications

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