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The repertoire of mutational signatures in childhood cancer - Nature Cancer

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The repertoire of mutational signatures in childhood cancer - Nature Cancer

Somatic mutations in cancer genomes are caused by multiple mutational processes, each generating characteristic mutational signatures. Our systematic mutational signature analysis of single base substitutions and small insertions and deletions in pediatric cancers indicates that the contribution of signatures of homologous recombination repair defect is limited and identifies a leukemia-specific signature.

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The repertoire of mutational signatures in childhood cancer - Nature Cancer

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The repertoire of mutational signatures in childhood cancer - Nature Cancer

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