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Meta-analysis of harmonized brain transcriptomics data prioritizes therapeutic target genes - Nature Genetics

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Meta-analysis of harmonized brain transcriptomics data prioritizes therapeutic target genes - Nature Genetics

A meta-analysis of harmonized human brain RNA-seq datasets creates expression quantitative trait locus (eQTL) maps for multiple ancestries and brain regions, predicts cell-type-dependent eQTLs and produces gene networks. This prioritizes genes for multiple brain-related diseases, serving as a promising step toward the identification of central nervous system (CNS) drug targets.

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Meta-analysis of harmonized brain transcriptomics data prioritizes therapeutic target genes - Nature Genetics

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Meta-analysis of harmonized brain transcriptomics data prioritizes therapeutic target genes - Nature Genetics

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