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Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells - Nature

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Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells - Nature

Down's syndrome (DS) presents with a constellation of cardiac, neurocognitive and growth impairments. Individuals with DS are also prone to severe infections and autoimmunity including thyroiditis, type 1 diabetes, coeliac disease and alopecia areata1,2. Here, to investigate the mechanisms underlying autoimmune susceptibility, we mapped the soluble and cellular immune landscape of individuals with DS.

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motivation inspiration cd11c b cells syndrome autoimmunity cytokines cells health cell biology biology microbiology

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Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells - Nature

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Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells - Nature

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