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Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer - Nature

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Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer - Nature

Pancreatic ductal adenocarcinoma (PDAC) is expected to be the second most deadly cancer by 2040, owing to the high incidence of metastatic disease and limited responses to treatment1,2. Less than half of all patients respond to the primary treatment for PDAC, chemotherapy3,4, and genetic alterations alone cannot explain this5. Diet is an environmental factor that can influence the response to therapies, but its role in PDAC is unclear.

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Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer - Nature

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Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer - Nature

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