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Nuclear condensates in YAP1-driven ependymoma - Nature Cell Biology

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Nuclear condensates in YAP1-driven ependymoma - Nature Cell Biology

An ependymoma subtype is driven by fusion proteins related to the transcriptional regulator YAP1. Research now shows that localization of these fusion proteins within nuclear condensates is necessary and sufficient for tumour formation through the activation of various genetic and epigenetic oncogenic mechanisms.

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Nuclear condensates in YAP1-driven ependymoma - Nature Cell Biology

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Nuclear condensates in YAP1-driven ependymoma - Nature Cell Biology

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