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Advancing CAR T cell therapy through the use of multidimensional omics data - Nature Reviews Clinical Oncology
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Despite the notable success of chimeric antigen receptor (CAR) T cell therapies in the treatment of certain haematological malignancies, challenges remain in optimizing CAR designs and cell products, improving response rates, extending the durability of remissions, reducing toxicity and broadening the utility of this therapeutic modality to other cancer types.
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