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Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division - Nature Cell Biology

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Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division - Nature Cell Biology

The control of cell shape during cytokinesis requires a precise regulation of mechanical properties of the cell cortex. Only few studies have addressed the mechanisms underlying the robust production of unequal-sized daughters during asymmetric cell division. Here we report that unequal daughter-cell sizes resulting from asymmetric sensory organ precursor divisions in Drosophila are controlled by the relative amount of cortical branched Actin between the two cell poles.

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Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division - Nature Cell Biology

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Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division - Nature Cell Biology

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