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A sleep-active basalocortical pathway crucial for generation and maintenance of chronic pain - Nature Neuroscience

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A sleep-active basalocortical pathway crucial for generation and maintenance of chronic pain - Nature Neuroscience

Poor sleep is associated with the risk of developing chronic pain, but how sleep contributes to pain chronicity remains unclear. Here we show that following peripheral nerve injury, cholinergic neurons in the anterior nucleus basalis (aNB) of the basal forebrain are increasingly active during nonrapid eye movement (NREM) sleep in a mouse model of neuropathic pain.

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A sleep-active basalocortical pathway crucial for generation and maintenance of chronic pain - Nature Neuroscience

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A sleep-active basalocortical pathway crucial for generation and maintenance of chronic pain - Nature Neuroscience

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