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An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells - Nature Immunology

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An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells - Nature Immunology

Immunoglobulin A (IgA) secretion by plasma cells, terminally differentiated B cells residing in the intestinal lamina propria, assures microbiome homeostasis and protects the host against enteric infections. Exposure to diet-derived and commensal-derived signals provides immune cells with organizing cues that instruct their effector function and dynamically shape intestinal immune responses at the mucosal barrier.

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An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells - Nature Immunology

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An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells - Nature Immunology

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