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Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales - Nature Chemical Biology

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Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales - Nature Chemical Biology

Methanogenic archaea are main actors in the carbon cycle but are sensitive to reactive sulfite. Some methanogens use a sulfite detoxification system that combines an F420H2-oxidase with a sulfite reductase, both of which are proposed precursors of modern enzymes. Here, we present snapshots of this coupled system, named coenzyme F420-dependent sulfite reductase (Group I Fsr), obtained from two marine methanogens.

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Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales - Nature Chemical Biology

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Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales - Nature Chemical Biology

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