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Functional T cells are capable of supernumerary cell division and longevity - Nature

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Functional T cells are capable of supernumerary cell division and longevity - Nature

Differentiated somatic mammalian cells putatively exhibit species-specific division limits that impede cancer but may constrain lifespans1–3. To provide immunity, transiently stimulated CD8+ T cells undergo unusually rapid bursts of numerous cell divisions, and then form quiescent long-lived memory cells that remain poised to reproliferate following subsequent immunological challenges. Here we addressed whether T cells are intrinsically constrained by chronological or cell-division limits.

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Functional T cells are capable of supernumerary cell division and longevity - Nature

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Functional T cells are capable of supernumerary cell division and longevity - Nature

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