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Adaptor protein HIP-55-mediated signalosome protects against ferroptosis in myocardial infarction - Cell Death & Differentiation

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Adaptor protein HIP-55-mediated signalosome protects against ferroptosis in myocardial infarction - Cell Death & Differentiation

Ischemic heart disease is a leading cause of death worldwide. Myocardial infarction (MI) results in cardiac damage due to cell death and insufficient cardiomyocyte self-renewal. Ferroptosis, a novel type of cell death, has recently been shown as a key cause of cardiomyocyte death after MI. However, the complicated regulation mechanisms involved in ferroptosis, especially how ferroptosis is integrated into classical cell survival/death pathways, are still unclear.

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Adaptor protein HIP-55-mediated signalosome protects against ferroptosis in myocardial infarction - Cell Death & Differentiation

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Adaptor protein HIP-55-mediated signalosome protects against ferroptosis in myocardial infarction - Cell Death & Differentiation

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