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General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions - Cell Death & Differentiation

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General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions - Cell Death & Differentiation

Taf4 (TATA-box binding protein-associated factor 4) is a subunit of the general transcription factor TFIID, a component of the RNA polymerase II pre-initiation complex that interacts with tissue-specific transcription factors to regulate gene expression. Properly regulated gene expression is particularly important in the intestinal epithelium that is constantly renewed from stem cells.

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motherhood polycomb stem cell cells differentiation transcription cell biology biology microbiology

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General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions - Cell Death & Differentiation

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General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions - Cell Death & Differentiation

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