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Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets - Nature Metabolism

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Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets - Nature Metabolism

Human pluripotent stem cell-derived islets (hPSC islets) are a promising alternative to primary human islets for the treatment of insulin-deficient diabetes. We previously demonstrated the feasibility of this approach in nonhuman primates; however, the therapeutic effects of hPSC islets can be limited by the maladaptive processes at the transplantation site.

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Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets - Nature Metabolism

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Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets - Nature Metabolism

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