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Dissecting MENIN in bivalent gene regulation - Nature Cell Biology

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Dissecting MENIN in bivalent gene regulation - Nature Cell Biology

Bivalent genes are regulated by a balance between repressive Polycomb group proteins and activating trithorax group proteins. A new study has revealed that MENIN, an accessory component of KMT2A/B methyltransferase complexes, has an unorthodox role in repressing bivalent genes, alongside Polycomb repressive complexes.

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Dissecting MENIN in bivalent gene regulation - Nature Cell Biology

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Dissecting MENIN in bivalent gene regulation - Nature Cell Biology

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