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Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation - Nature Immunology

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Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation - Nature Immunology

Diverse inflammasome stimuli recruit NLRP3 to dysfunctional endosomes via interactions with lipids that accumulate in excess on these organelles. Excess lipid detection may be a common principle that explains NLRP3 function in health and disease.

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Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation - Nature Immunology

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Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation - Nature Immunology

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