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The role of the lateral orbitofrontal cortex in creating cognitive maps - Nature Neuroscience
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We use mental models of the world—cognitive maps—to guide behavior. The lateral orbitofrontal cortex (lOFC) is typically thought to support behavior by deploying these maps to simulate outcomes, but recent evidence suggests that it may instead support behavior by underlying map creation. We tested between these two alternatives using outcome-specific devaluation and a high-potency chemogenetic approach.
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