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PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression - Nature Communications

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PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression - Nature Communications

The progression of cancer from localized to metastatic disease is the primary cause of morbidity and mortality. The interplay between the tumor and its microenvironment is the key driver in this process of tumor progression. In order for tumors to progress and metastasize they must reprogram the cells that make up the microenvironment to promote tumor growth and suppress endogenous defense systems, such as the immune and inflammatory response.

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PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression - Nature Communications

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PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression - Nature Communications

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