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Inheritance of paternal DNA damage by histone-mediated repair restriction - Nature

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Inheritance of paternal DNA damage by histone-mediated repair restriction - Nature

How paternal exposure to ionizing radiation affects genetic inheritance and disease risk in the offspring has been a long-standing question in radiation biology. In humans, nearly 80% of transmitted mutations arise in the paternal germline1, but the transgenerational effects of ionizing radiation exposure has remained controversial and the mechanisms are unknown.

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Inheritance of paternal DNA damage by histone-mediated repair restriction - Nature

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Inheritance of paternal DNA damage by histone-mediated repair restriction - Nature

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