@curator

1 year ago

Article

A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis - Nature Communications

Rating: 0.0

Likes: 1

Library: 1

A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis - Nature Communications

Phagocytic clearance of dying cells, termed efferocytosis, is essential for maintaining tissue homeostasis, yet our understanding of efferocytosis regulation remains incomplete. Here we perform a FACS-based, genome-wide CRISPR knockout screen in primary mouse macrophages to search for novel regulators of efferocytosis. The results show that Wdfy3 knockout in macrophages specifically impairs uptake, but not binding, of apoptotic cells due to defective actin disassembly.

Rate This Post

Rate The Educational Value

Rate The Ease of Understanding and Presentation

Interesting or Boring? Rate the Entertainment Value

Related Topics

efferocytosis macrophage

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Add articles, eBooks or videos to your Library.
You can revisit, watch or read your favorite items later

Learning is Fun!

Close

Unlocking the Power of Knowledge
for Humanity's Progress

By harnessing the power of Artificial Intelligence, Boostlane is changing the way we engage with information, connect with experts, and foster personal growth.

Explore Topics,
Discover Ideas,
Share knowledge,
Learn from Experts

Boostlane is a media platform that aims to revolutionize how we research, discover, and learn about our favorite topics

Boostlane relies on the power of Artificial Intelligence and a Community of Researchers to curate and deliver reliable, insightful, and purposeful knowledge

Support a platform focused on research and useful knowledge.
Create personalized feeds.
Follow your favorite topics and learn something new every day.
Learn with the assistance of people and Artificial Intelligence Systems.
Use innovative features designed to organize information and foster personal growth.
Collect your favorite media in your private Library.

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Unlocking the Power of Knowledge
for Humanity's Progress

By harnessing the power of Artificial Intelligence, Boostlane is changing the way we engage with information, connect with experts, and foster personal growth.

Explore Topics,
Discover Ideas,
Share knowledge,
Learn from Experts

Boostlane is a media platform that aims to revolutionize how we research, discover, and learn about our favorite topics

Boostlane relies on the power of Artificial Intelligence and a Community of Researchers to curate and deliver reliable, insightful, and purposeful knowledge

Support a platform focused on research and useful knowledge.
Create personalized feeds.
Follow your favorite topics and learn something new every day.
Learn with the assistance of people and Artificial Intelligence Systems.
Use innovative features designed to organize information and foster personal growth.
Collect your favorite media in your private Library.

A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis - Nature Communications

Rate This Post

Related Topics

Comments

Media:

My Account:

Boostlane:

Select a Category

Topics Trending Today

Recommended Media

Boostlane Reward System

Unlocking the Power of Knowledge
for Humanity's Progress

Quick Links

Select a Locale

Unlocking the Power of Knowledge
for Humanity's Progress

A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis - Nature Communications

Rate This Post

Related Topics

Comments

Media:

My Account:

Boostlane:

Select a Category

Topics Trending Today

Recommended Media

Boostlane Reward System

Unlocking the Power of Knowledge for Humanity's Progress

Quick Links

Select a Locale

Unlocking the Power of Knowledge for Humanity's Progress

Unlocking the Power of Knowledge
for Humanity's Progress

Unlocking the Power of Knowledge
for Humanity's Progress