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BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network - Nature

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BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network - Nature

Inhibition of the tumour suppressive function of p53 (encoded by TP53) is paramount for cancer development in humans. However, p53 remains unmutated in the majority of cases of glioblastoma (GBM)—the most common and deadly adult brain malignancy1,2. Thus, how p53-mediated tumour suppression is countered in TP53 wild-type (TP53WT) GBM is unknown.

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BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network - Nature

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BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network - Nature

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