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Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics - Nature Nanotechnology

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Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics - Nature Nanotechnology

T cells play a determining role in the immunomodulation and prognostic evaluation of cancer treatments relying on immune activation. While specific biomarkers determine the population and distribution of T cells in tumours, the in situ activity of T cells is less studied. Here we designed T-cell-targeting fusogenic liposomes to regulate and quantify the activity of T cells by exploiting their surface redox status as a chemical target.

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health business cells cancer redox activity membrane cell biology biology microbiology

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Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics - Nature Nanotechnology

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Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics - Nature Nanotechnology

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