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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma - Cell Death & Differentiation

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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma - Cell Death & Differentiation

Anillin (ANLN) is a mitosis-related protein that promotes contractile ring formation and cytokinesis, but its cell cycle-dependent degradation mechanisms in cancer cells remain unclear. Here, we show that high expression of ANLN promotes cytokinesis and proliferation in esophageal squamous cell carcinoma (ESCC) cells and is associated with poor prognosis in ESCC patients.

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degradation carcinoma cell health cell biology biology microbiology

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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma - Cell Death & Differentiation

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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma - Cell Death & Differentiation

Rate This Post

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Comments

Media:

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Recommended Media

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Unlocking the Power of Knowledge for Humanity's Progress

Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
for Humanity's Progress