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Profiling the epigenetic landscape of the antigen receptor repertoire: the missing epi-immunogenomics data - Nature Methods

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Profiling the epigenetic landscape of the antigen receptor repertoire: the missing epi-immunogenomics data - Nature Methods

High-resolution sequencing methods that capture the epigenetic landscape within the T cell receptor (TCR) gene loci are pivotal for a fundamental understanding of the epigenetic regulatory mechanisms of the TCR repertoire. In our opinion, filling the gaps in our understanding of the epigenetic mechanisms regulating the TCR repertoire will benefit the development of strategies that can modulate the TCR repertoire composition by leveraging the dynamic nature of epigenetic modifications.

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Profiling the epigenetic landscape of the antigen receptor repertoire: the missing epi-immunogenomics data - Nature Methods

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Profiling the epigenetic landscape of the antigen receptor repertoire: the missing epi-immunogenomics data - Nature Methods

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