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Soluble guanylyl cyclase in platelets keeps atherosclerosis at bay - Nature Cardiovascular Research

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Soluble guanylyl cyclase in platelets keeps atherosclerosis at bay - Nature Cardiovascular Research

The contribution of platelets to atherothrombosis is well established. Accumulating genome-wide association studies have revealed several variants of genes encoding molecules along the nitric oxide (NO)–soluble guanylyl cyclase (sGC)–cyclic guanosine-3′,5′-monophosphate (cGMP) pathway that are associated with increased risk of coronary artery disease; however, the cell types and functional impact of these risk variants remain poorly understood. Mauersberger et al.

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Soluble guanylyl cyclase in platelets keeps atherosclerosis at bay - Nature Cardiovascular Research

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Soluble guanylyl cyclase in platelets keeps atherosclerosis at bay - Nature Cardiovascular Research

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