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CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization - Nature

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CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization - Nature

Multilocular adipocytes are a hallmark of thermogenic adipose tissue1,2, but the factors that enforce this cellular phenotype are largely unknown. Here, we show that an adipocyte-selective product of the Clstn3 locus (CLSTN3β) present in only placental mammals facilitates the efficient use of stored triglyceride by limiting lipid droplet (LD) expansion.

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CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization - Nature

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CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization - Nature

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