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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants - Nature Genetics

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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants - Nature Genetics

The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) comprising 181,522 cases among 1,165,690 participants of predominantly European ancestry. We detected 241 associations, including 30 new loci. Cross-ancestry meta-analysis with a Japanese GWAS yielded 38 additional new loci.

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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants - Nature Genetics

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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants - Nature Genetics

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