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Ubiquitinated plasma membrane proteins are specifically recognized by the TPLATE complex - Nature Plants

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Ubiquitinated plasma membrane proteins are specifically recognized by the TPLATE complex - Nature Plants

The TPLATE complex (TPC) is an ancient multi-subunit adaptor complex, essential for clathrin-mediated endocytosis in plants. We found that the evolutionary specific SH3 domain on the large TPC subunit, TASH3, recognizes ubiquitinated cargo proteins at the plasma membrane, providing a link between endocytosis and internalization of ubiquitinated proteins.

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Ubiquitinated plasma membrane proteins are specifically recognized by the TPLATE complex - Nature Plants

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Ubiquitinated plasma membrane proteins are specifically recognized by the TPLATE complex - Nature Plants

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