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Mitochondrial RNA stimulates heat production in young adipocytes to reduce obesity - Nature Metabolism

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Mitochondrial RNA stimulates heat production in young adipocytes to reduce obesity - Nature Metabolism

Mitochondria of young adipocytes release RNA molecules that serve as signals to stimulate the transcription of nuclear-encoded genes for mitobiogenesis and thermogenesis. Mitochondrial RNA (mtRNA) efflux thus establishes retrograde mitochondria–nucleus signalling and triggers heat production from fat. Stimulating this signalling protects against obesity in mice.

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Mitochondrial RNA stimulates heat production in young adipocytes to reduce obesity - Nature Metabolism

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Mitochondrial RNA stimulates heat production in young adipocytes to reduce obesity - Nature Metabolism

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