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Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling - Cellular & Molecular Immunology

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Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling - Cellular & Molecular Immunology

The most abundant immunoglobulin present in the human body is IgA. It has the highest concentrations at the mucosal lining and in biofluids such as milk and is the second most abundant class of antibodies in serum. We assessed the structural diversity and clonal repertoire of IgA1-containing molecular assemblies longitudinally in human serum and milk from three donors using a mass spectrometry-based approach.

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Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling - Cellular & Molecular Immunology

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Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling - Cellular & Molecular Immunology

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