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The endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo - Nature Plants

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The endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo - Nature Plants

Endocytosis controls the perception of stimuli by modulating protein abundance at the plasma membrane. In plants, clathrin-mediated endocytosis is the most prominent internalization pathway and relies on two multimeric adaptor complexes, the AP-2 and the TPLATE complex (TPC). Ubiquitination is a well-established modification triggering endocytosis of cargo proteins, but how this modification is recognized to initiate the endocytic event remains elusive.

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The endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo - Nature Plants

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The endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo - Nature Plants

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