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Mechanism of cyclic β-glucan export by ABC transporter Cgt of Brucella - Nature Structural & Molecular Biology

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Mechanism of cyclic β-glucan export by ABC transporter Cgt of Brucella - Nature Structural & Molecular Biology

Polysaccharides play critical roles in bacteria, including the formation of protective capsules and biofilms and establishing specific host cell interactions. Their transport across membranes is often mediated by ATP-binding cassette (ABC) transporters, which utilize ATP to translocate diverse molecules. Cyclic β-glucans (CβGs) are critical for host interaction of the Rhizobiales, including the zoonotic pathogen Brucella.

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Mechanism of cyclic β-glucan export by ABC transporter Cgt of Brucella - Nature Structural & Molecular Biology

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Mechanism of cyclic β-glucan export by ABC transporter Cgt of Brucella - Nature Structural & Molecular Biology

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