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Mitochondrial RNA stimulates beige adipocyte development in young mice - Nature Metabolism

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Mitochondrial RNA stimulates beige adipocyte development in young mice - Nature Metabolism

Childhood obesity is a serious public health crisis and a critical factor that determines future obesity prevalence. Signals affecting adipocyte development in early postnatal life have a strong potential to trigger childhood obesity; however, these signals are still poorly understood. We show here that mitochondrial (mt)RNA efflux stimulates transcription of nuclear-encoded genes for mitobiogenesis and thermogenesis in adipocytes of young mice and human infants.

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Mitochondrial RNA stimulates beige adipocyte development in young mice - Nature Metabolism

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Mitochondrial RNA stimulates beige adipocyte development in young mice - Nature Metabolism

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