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Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres - Cell Death & Disease

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Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres - Cell Death & Disease

Telomerase reactivation is one of the hallmarks of cancer, which plays an important role in cellular immortalization and the development and progression of the tumor. Chemical telomerase inhibitors have been shown to trigger replicative senescence and apoptotic cell death both in vitro and in vivo. Due to its upregulation in various cancers, telomerase is considered a potential target in cancer therapy.

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telomerase dna telomere cell death cell health cell biology biology microbiology

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Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres - Cell Death & Disease

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Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres - Cell Death & Disease

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