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Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells - Cell Death & Disease

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Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells - Cell Death & Disease

Ciclopirox (CPX), an antifungal drug, has recently been identified as a promising agent for cancer treatment. However, the effects and underlying mechanism of CPX as an antitumor agent of gastric cancer (GC) remain largely unknown. Here, we found that CPX dramatically suppresses GC xenograft growth in vitro via inhibiting proliferation and stimulating autophagic cell death rather than apoptosis.

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motivation inspiration ciclopirox growth cell death cancer gastric cancer stat3 cells cell biology biology microbiology health

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Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells - Cell Death & Disease

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Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells - Cell Death & Disease

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
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