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Power and optimal study design in iPSC-based brain disease modelling - Molecular Psychiatry

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Power and optimal study design in iPSC-based brain disease modelling - Molecular Psychiatry

Studies using induced pluripotent stem cells (iPSCs) are gaining momentum in brain disorder modelling, but optimal study designs are poorly defined. Here, we compare commonly used designs and statistical analysis for different research aims. Furthermore, we generated immunocytochemical, electrophysiological, and proteomic data from iPSC-derived neurons of five healthy subjects, analysed data variation and conducted power simulations.

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Power and optimal study design in iPSC-based brain disease modelling - Molecular Psychiatry

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Power and optimal study design in iPSC-based brain disease modelling - Molecular Psychiatry

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