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Image prediction of disease progression for osteoarthritis by style-based manifold extrapolation - Nature Machine Intelligence

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Image prediction of disease progression for osteoarthritis by style-based manifold extrapolation - Nature Machine Intelligence

Disease-modifying management aims to prevent deterioration and progression of the disease, and not just to relieve symptoms. We present a solution for the management by a methodology that allows the prediction of progression risk and morphology in individuals using a latent extrapolation approach. To this end, we combined a regularized generative adversarial network and a latent nearest neighbour algorithm for joint optimization to generate plausible images of future time points.

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Image prediction of disease progression for osteoarthritis by style-based manifold extrapolation - Nature Machine Intelligence

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Image prediction of disease progression for osteoarthritis by style-based manifold extrapolation - Nature Machine Intelligence

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