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Topological morphogenesis of neuroepithelial organoids - Nature Physics

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Topological morphogenesis of neuroepithelial organoids - Nature Physics

Animal organs exhibit complex topologies involving cavities and tubular networks, which underlie their form and function1–3. However, how topology emerges during the development of organ shape, or morphogenesis, remains elusive. Here we combine tissue reconstitution and quantitative microscopy to show that tissue topology and shape is governed by two distinct modes of topological transitions4,5.

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Topological morphogenesis of neuroepithelial organoids - Nature Physics

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Topological morphogenesis of neuroepithelial organoids - Nature Physics

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