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Chromatin oxygen sensing by histone H3 prolyl hydroxylation - Nature Genetics

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Chromatin oxygen sensing by histone H3 prolyl hydroxylation - Nature Genetics

A new study identifies prolyl hydroxylation of histone H3 as a signal for the recruitment of KDM5A, altering H3K4me3 and gene expression. H3P16oh is independent of the HIF hypoxia-sensing pathway and provides a further layer of complexity to oxygen-sensitive chromatin modifications.

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Chromatin oxygen sensing by histone H3 prolyl hydroxylation - Nature Genetics

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Chromatin oxygen sensing by histone H3 prolyl hydroxylation - Nature Genetics

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