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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein - Molecular Psychiatry

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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein - Molecular Psychiatry

Coronavirus disease-2019 (COVID-19) is primarily a respiratory disease, however, an increasing number of reports indicate that SARS-CoV-2 infection can also cause severe neurological manifestations, including precipitating cases of probable Parkinson's disease. As microglial NLRP3 inflammasome activation is a major driver of neurodegeneration, here we interrogated whether SARS-CoV-2 can promote microglial NLRP3 inflammasome activation.

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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein - Molecular Psychiatry

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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein - Molecular Psychiatry

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
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