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Modifying dolutegravir to PrEPare for long life - Communications Biology

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Modifying dolutegravir to PrEPare for long life - Communications Biology

Anti-retroviral therapy with drugs like dolutegravir is a powerful tool in both the treatment and prevention of HIV, but is limited by strict adherence to a daily therapeutic regimen. In a recent study, Deodhar, Sillman, and colleagues developed a dolutegravir prodrug that offers long-lasting protection against HIV infection, with the potential to dramatically improve anti-retroviral therapy efficacy.

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Modifying dolutegravir to PrEPare for long life - Communications Biology

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Modifying dolutegravir to PrEPare for long life - Communications Biology

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