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Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification - Nature Chemistry

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Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification - Nature Chemistry

Identification and quantification of synthetic polymers in complex biological milieu are crucial for delivery, sensing and scaffolding functions, but conventional techniques based on imaging probe labellings only afford qualitative results. Here we report modular construction of precise sequence-defined amphiphilic polymers that self-assemble into digital micelles with contour lengths strictly regulated by oligourethane sequences.

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Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification - Nature Chemistry

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Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification - Nature Chemistry

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