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Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces - Nature

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Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces - Nature

Emerging studies indicate that cooperation between neurons and immune cells regulates antimicrobial immunity, inflammation and tissue homeostasis. For example, a neuronal rheostat provides excitatory or inhibitory signals that control the functions of tissue-resident group 2 innate lymphoid cells (ILC2s) at mucosal barrier surfaces1–4. ILC2s express NMUR1, a receptor for neuromedin U (NMU), which is a prominent cholinergic neuropeptide that promotes ILC2 responses5–7.

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Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces - Nature

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Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces - Nature

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