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Proteome effects of genome-wide single gene perturbations - Nature Communications

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Proteome effects of genome-wide single gene perturbations - Nature Communications

Protein abundance is controlled at the transcriptional, translational and post-translational levels, and its regulatory principles are starting to emerge. Investigating these principles requires large-scale proteomics data and cannot just be done with transcriptional outcomes that are commonly used as a proxy for protein abundance. Here, we determine proteome changes resulting from the individual knockout of 3308 nonessential genes in the yeast Schizosaccharomyces pombe.

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Proteome effects of genome-wide single gene perturbations - Nature Communications

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Proteome effects of genome-wide single gene perturbations - Nature Communications

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