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Brain milieu induces early microglial maturation through the BAX-Notch axis - Nature Communications

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Brain milieu induces early microglial maturation through the BAX-Notch axis - Nature Communications

Microglia are derived from primitive myeloid cells and gain their early identity in the embryonic brains. However, the mechanism by which the brain milieu confers microglial maturation signature remains elusive. Here, we demonstrate that the baxcq55 zebrafish and Baxtm1Sjk mouse embryos exhibit similarly defective early microglial maturation.

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Brain milieu induces early microglial maturation through the BAX-Notch axis - Nature Communications

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Brain milieu induces early microglial maturation through the BAX-Notch axis - Nature Communications

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